Barcelona, Spain (SportsNetwork.com) - Barcelona and Real Madrid will reunite at Camp Nou on Sunday for the latest installment of El Clasico, this time with massive title implications.

The Catalans enter the weekend atop the La Liga table with 65 points from 27 matches, one point better than Real Madrid.

The result of Sunday's affair could go a long way toward deciding the destination of the title, giving both sides plenty of motivation to collect three points.

Barcelona, though, will be especially eager to come away victorious after the club suffered a humiliating 3-1 loss to Madrid at the Bernabeu earlier in the season.

The Catalans took the lead after only four minutes through Neymar, but it all went pear-shaped from there as Cristiano Ronaldo, Pepe and Karim Benzema produced a goal apiece to complete Madrid's comeback.

The Galacticos also enter the contest on greater rest as Barcelona was forced into a midweek Champions League clash against Manchester City, though the Catalans did not expend a great deal of energy, dictating play and letting the ball do the work in a dominant 1-0 victory.

Real Madrid claimed a 2-0 victory over Levante in its last La Liga outing to snap a three-game winless run across all competitions, but it remains to be seen whether that result was a flash in the pan or if it's a signal that Carlo Ancelotti's men are regaining their form.

Atletico Madrid has hit a bit of a rough patch as a run of three successive draws dropped the reigning La Liga champions to fourth place in the table with 56 points.

Diego Simeone's men were forced to play 120 minutes of football on Tuesday after their Champions League tie went into extra time, but they will need to regroup in time for Saturday's clash against Getafe at the Vicente Calderon.

Valencia, meanwhile, has capitalized on Atletico's sputtering form, picking up a 4-0 win at Elche on Friday to improve to 60 points on the season.

Sevilla enters the weekend in fifth place with 52 points and will face a massive test on Sunday when it travels to El Madrigal to take on sixth-place Villarreal.

Also on Sunday, Deportivo will host Espanyol at the Riazor while Real Sociedad will welcome lowly Cordoba to the Anoeta.

Athletic Bilbao has been in sublime form of late, rattling off four successive league victories, including a narrow defeat of Real Madrid. The Basque club will be out to make it five wins in a row on Saturday when it welcomes Almeria to San Mames.

Malaga will hope to reignite its quest for European football for next season with maximum points at Rayo Vallecano on Saturday while Levante will host Celta Vigo at the Ciutat de Valencia and Eibar heads to Los Carmenes to face Granada.