Andrew Luck threw for four touchdowns and the Colts' defense kept Eli Manning and the Giants off balance in Indianapolis' 40-24 romp on Monday night.

With his franchise-record seventh consecutive 300-yard game, Luck led the Colts (6-3) to a lopsided win one week after a 51-34 loss to Pittsburgh. Unlike the way Steelers quarterback Ben Roethlisberger toyed with their defense in that game, the Colts didn't let Manning get going in handing New York (3-5) its third straight defeat.

Luck hit Coby Fleener for a 32-yard TD in the first half. He had scoring throws of 31 yards to T.Y. Hilton, 40 yards to Reggie Wayne and 2 yards to Dwayne Allen in the third period.

Adam Vinatieri added four field goals and is perfect on 20 tries this year.

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