Natalie Achonwa got Notre Dame going early and never let up as she finished with 23 points and Jewell Loyd added 20 to lead the Fighting Irish to an 89-72 victory over Oklahoma State in a regional semifinal on Saturday.
Notre Dame (35-0) is a victory away from its fifth straight Final Four berth, while the Cowgirls (25-9) missed a chance to advance to a regional final for the first time in school history. They fell to 0-3 in regional semifinals.
To get to the Final Four, the Irish will have to beat Baylor, the last team to knockoff Notre Dame at home.
The Irish jumped to a 14-0 lead in the opening 3:31, capped by a three-point play by Achonwa, as the Cowgirls missed their first six shots. The Cowgirls later used a 7-0 run to cut the lead to 24-14, but that was as close as they got.