Louis Vasquez and Manny Ramirez were guards at Texas Tech together, a position neither of them will play in Peyton Manning's homecoming game Sunday night.
Ramirez is a first-year starter at center after injuries sidelined J.D. Walton and Dan Koppen and Vasquez is set to make his first career start at right guard in place of Orlando Franklin when the Denver Broncos (6-0) take on the Indianapolis Colts (4-2).
Vasquez slid over when Franklin sprained his left knee and ankle in a pileup in the end zone against Jacksonville last week. That marked the first time Vasquez ever played at right tackle, although he filled in occasionally at left tackle in college.