Updated

Five-time champion Roger Federer moved on in straights sets Tuesday at the U.S. Open.

The seventh-seeded former world No. 1 great Federer handled Slovenian Grega Zemlja 6-3, 6-2, 7-5 at Arthur Ashe Stadium in a match that was postponed because of rain on Monday night.

The 17-time Grand Slam titlist was the tennis king of New York from 2004-08 and runner-up in 2009.

Up next for the Swiss icon will be Argentine Carlos Berlocq.

Fifth-seeded former Wimbledon runner-up Tomas Berdych, of the Czech Republic, leveled 31-year-old Italian Paolo Lorenzi, 6-1, 6-4, 6-1, while top American John Isner reached the second round, as the 13th-seeded 6-foot-9 slugger was efficient in dismantling helpless Italian Filippo Volandri, 6-0, 6-2, 6-3, in only 1 hour, 16 minutes on the Grandstand court. The massive-serving Isner fired 16 aces on Day 2.

The surging Isner recently titled in Atlanta and was a hardcourt runner-up in Washington, D.C., and at an ATP Masters 1000 event in Cincinnati.

Meanwhile, 10th-seeded 6-foot-5 rising Canadian Milos Raonic handled diminutive Italian Thomas Fabbiano, 6-3, 7-6 (8-6), 6-3 and 35-year-old 12th- seeded German Tommy Haas eased past Frenchman Paul-Henri Mathieu, 6-4, 6-4, 6-1, on a warm, breezy day at the USTA Billie Jean King National Tennis Center. The powerful Raonic unleashed 28 aces, compared to zero by the overmatched Fabbiano.

A surprising Day-2 upset came when 30-year-old Argentine qualifier Maximo Gonzalez upended hurting 14th-seeded 6-foot-8 Pole Jerzy Janowicz, 6-4, 6-4, 6-2.

Janowicz, who was slowed by a back injury on Tuesday, reached his first- ever Grand Slam semifinal at Wimbledon just last month.

"I could barely walk, I couldn't practice," Janowicz said. "I couldn't find a normal position to sleep."

"I'm so unlucky every time in New York," said Janowicz, who strained a leg muscle four days before the U.S. Open last year before going on to lose to a world No. 1,098 Dennis Novikov, then a UCLA sophomore, also in the opening round.

He joked, "Maybe I'm practicing too hard for New York."

A milder upset occurred when Uzbekistan's Denis Istomin tripped up 15th-seeded struggling Spaniard Nicolas Almagro, 6-3, 6-1, 4-6, 6-3.

Also on Tuesday, 22nd-seeded German Philipp Kohlschreiber whipped 17-year-old American Collin Altamirano, making his ATP-level debut, 6-1, 6-3, 6-1; Portuguese Joao Sousa erased 25th-seeded Bulgarian Grigor Dimitrov, 3-6, 6-3, 6-4, 5-7, 6-2; 26th-seeded American Sam Querrey bested Argentine Guido Pella, 7-6 (7-3), 4-6, 6-1, 6-2; and 31st-seeded quality Frenchman Julien Benneteau got past Poland's Michal Przysiezny, 6-4, 5-7, 6-4, 6-4.

Also advancing was French former top-10 star Gael Monfils, who drubbed Romanian Adrian Ungur, 6-1, 6-2, 6-0, to set-up a second-rounder with Isner.

In other matches involving Americans, Jack Sock was beating Philipp Petzschner 7-6 (7-2), 3-6, 5-2 when the German retired and Donald Young tattooed Slovak Martin Klizan, 6-1, 6-0, 6-1.