Serena Williams will begin her bid for a second French Open championship and 16th Grand Slam title overall by facing 83rd-ranked Anna Tatishvili in the first round.
A year ago in Paris, Williams lost her opening match to 111th-ranked Virginie Razzano, the American's only first-round loss in 50 career Grand Slam tournaments.
Williams is seeded No. 1 this year and is on a career-best 24-match winning streak. Tatishvili is 0-2 at Roland Garros.
Friday's draw for the clay-court major tournament set up these possible women's quarterfinals: Williams against No. 8 Angelique Kerber, defending champion Maria Sharapova against No. 7 Petra Kvitova, No. 3 Victoria Azarenka against 2011 champion Li Na, and No. 4 Agnieszka Radwanska against 2012 runner-up Sara Errani.
The tournament begins Sunday.