Updated

Right-hander Hiram Burgos takes the mound in his major- league debut on Saturday night when the Milwaukee Brewers host the Chicago Cubs in the middle game of a three-game series at Miller Park.

A 25-year-old from Puerto Rico, Burgos was the Brewers' minor-league pitcher of the year in 2012 after going 10-4 with a 1.95 earned run average in 28 appearances across three levels of play.

He struck out 153 batters and walked 49.

Burgos began 2013 at Triple-A Nashville and was 0-2 in three starts, but maintained a solid 2.70 earned run average.

It's the first time this season the Milwaukee rotation has required a fifth starter.

For the Cubs, righty Edwin Jackson tries for a fourth time for his first win with another new team.

Now 29, Jackson was 10-11 in 31 starts with Washington last season before signing a four-year, $52 million deal with the Cubs on Jan. 2.

He's three games under .500 (70-73) in 237 career appearances while pitching for eight combined teams - Tampa Bay, the Los Angeles Dodgers, the Chicago White Sox, Arizona, St. Louis, Washington, Detroit and the Cubs.

He dropped a 7-4 decision to Milwaukee on April 8 in Chicago after allowing five runs on eight hits in six innings,

In eight career starts against the Brewers, he's 3-3 with a 3.57 earned run average.

On Friday, Ryan Braun hit a three-run homer and Carlos Gomez added a solo shot as the Brewers defeated the Cubs, 5-4.

Jonathan Lucroy hit an RBI triple and Rickie Weeks had one hit and a run scored for the Brewers, who have won five straight overall and their last six at home versus the Cubs. Starter Marco Estrada (2-0) gave up three runs on seven hits and struck out four over six innings.

David DeJesus had two hits, including a two-run shot, and Luis Valbuena and Anthony Rizzo each hit solo home runs for Chicago, which has lost four of five.

Jeff Samardzija (1-3) yielded five runs -- four earned -- on six hits over seven innings and fanned four in defeat.

The teams split two games on April 8-9 in Chicago. Milwaukee won 13 of 17 games between the teams last season.