Pierria Henry scored 17 points and led Charlotte to a 71-67 upset victory over 11th-ranked Butler on Wednesday.
Willie Clayton and Chris Braswell scored 11 points apiece, while Darion Clark recorded 10 points and nine rebounds for the 49ers (18-6, 6-4 A-10), who came into the contest on a two-game losing streak.
Rotnei Clarke had a game-high 18 points for Butler (20-5, 7-3), which had its three-game winning streak snapped. Roosevelt Jones registered 17 points and nine rebounds.
With 3 1/2 minutes remaining in regulation, Charlotte held a 60-50 advantage.
However, Butler would then outscore the 49ers by a 17-8 margin, capped off by a three-pointer by Clarke that closed the deficit to 68-67 with just eight seconds remaining. Clarke scored 13 points during the swing.
Butler's Khyle Marshall then fouled Henry, who made his first free throw to give Charlotte a 69-67 edge. However, he missed the second and Butler's Chase Stigall grabbed the defensive rebound, allowing the Bulldogs to call a timeout with just three seconds left.
Stigall attempted to pass, but Victor Nickerson stole the ball and subsequently drew a foul with one second remaining. Nickerson made both of his free throws to put the game out of reach.
Charlotte held a 29-27 margin at halftime.
Butler was 10-of-29 from three-point range ... The Bulldogs had a 12-game home winning streak snapped.