Updated

Isaiah Anderson had a career-best 174 yards receiving and caught three long touchdown passes from Clint Chelf in his final home game, leading Oklahoma State to a 59-21 win against No. 23 Texas Tech on Saturday.

Zack Craig blocked a pair of punts, returning one for a touchdown, as the Cowboys (7-3, 5-2 Big 12) won their fourth straight in the series and the second in a row in decisive fashion. The Red Raiders' 66-6 loss in last season's game was the most lopsided defeat in the program's history.

Chelf passed for 229 yards in his second career start. J.W. Walsh, who had what coach Mike Gundy called a season-ending injury four weeks ago, ran for one touchdown and threw for another out of a short-yardage package.

Seth Doege threw for 230 yards with two interceptions and a single touchdown pass for Texas Tech (7-4, 4-4).