Bob and Mike Bryan will play for a fourth U.S. Open title.
The American twins beat Aisam-ul-Haq Qureshi of Pakistan and Jean-Julien Rojer of the Netherlands 6-3, 6-4 in the semifinals Thursday.
The second-seeded Bryans, who have won 11 Grand Slam championships, will face fifth-seeded Leander Paes and Radek Stepanek in Friday's final. Paes and Stepanek advanced when the Spanish team of Marcel Granollers and Marc Lopez retired in the first set.
Lopez has a calf injury that he'll get examined back in Spain. He and Granollers are supposed to play doubles in the Davis Cup semifinal against the United States next week.
Italy's Sara Errani and Roberta Vinci easily won their doubles semifinal match a day after facing each other in a singles quarterfinal.
The second-seeded French Open champs beat Nuria Llagostera Vives and Maria Jose Martinez Sanchez of Spain 6-3, 6-2.
Errani and Vinci will face third-seeded Andrea Hlavackova and Lucie Hradecka in Sunday's final. That pair, from the Czech Republic, defeated Hsieh Su-wei and Anabel Medina Garrigues, 7-6 (2), 6-4.
In singles, Errani defeated Vinci 6-2, 6-4 on Wednesday to become the first Italian woman to reach a semi at this tournament since the Open era began in 1968.