Pinch-hitter A.J. Pierzynski tied a White Sox record by homering in his fifth consecutive game, a go-ahead, two-run drive in the seventh inning off Jason Isringhausen that led Chicago over the Los Angeles Angels 4-2 Sunday.
With the Angels ahead 2-1, Isringhausen (3-2) relieved Dan Haren and allowed a leadoff single to Dayan Viciedo. Pierzynski hit for Tyler Flowers and hit a drive just out of the reach of a leaping Mike Trout in right-center field, Pierzynski's career-high 21st homer.
Nate Jones (5-0) allowed one run in two innings, Brett Myers pitched a scoreless eighth and Addison Reed struck out two in the ninth for his 18th save in 21 chances.
Chicago took two of three in the weekend series and has won nine of 12 games.