Tamika Catchings totaled 16 points and Roneeka Hodges added 15 as Indiana routed New York, 91-68.
Jeanette Pohlen had 12 points and Katie Douglas contributed 11 for the Fever, who remain atop the Eastern Conference with a 4-0 record.
Indiana, which matched its best start in team history, tied the franchise record for three-pointers made in a game, going 13-of-26 from beyond the arc.
Plenette Pierson's game-high 24 points and six rebounds wasn't enough for the Liberty, who have opened the year with five straight losses.
The difference in the contest was made in the second quarter, claimed by Indiana with 29 points to 16 for New York. The Liberty also scored just seven points in the fourth.