CC Sabathia struck out seven batters over 7 1/3 innings and the New York Yankees got a career-high three RBI from Chris Stewart in an 8-3 victory over Minnesota.
Sabathia (1-0), who gave up four hits and three runs, is undefeated in his last 10 regular-season and postseason starts against the Twins (since August 3, 2007), going 9-0 over the span.
Stewart highlighted a four-run third with the go-ahead two-run single. Andruw Jones belted a solo homer and Derek Jeter knocked in two runs as part of a 13- hit attack.
The Twins, who took the opener of this four-game set on Monday, got a homer from Josh Willingham.
Francisco Liriano (0-2) allowed seven hits and five runs over 2 1/3 innings and saw his ERA rise to 11.91.
Twins center fielder Denard Span and manager Ron Gardenhire were ejected in the top of the third inning.