Glory Johnson recorded her ninth double- 61.
Ariel Massengale added 14 points, five rebounds and four assists while Shekinna Stricklen finished with 11 points and 10 rebounds for the Lady Volunteers (17-6, 8-2 SEC), who bounced back from a loss to South Carolina on Thursday.
Camille Glymph netted 13 points to lead Auburn (11-13, 3-8), which turned the ball over 23 times.
With the game tied at 14 early on, the Lady Vols used a 7-0 run to give them a lead they didn't relinquish. Tennessee took a 44-31 advantage into the locker room.
The Lady Vols limited Auburn to just 37 percent shooting in the second half as Tennessee coasted to the easy win.