There is one less unbeaten team in major college basketball.
Rodney McGruder scored 20 points and Will Spradling added 14, as 23rd-ranked Kansas State handed No. 7 Missouri its first loss of the season with a 75-59 decision at Bramlage Coliseum.
The Wildcats (12-2, 1-1 Big 12) bounced back nicely from a 67-49 setback at 14th-ranked Kansas on Wednesday and won for the seventh time in their last eight games. They'll get another crack at an unbeaten team in their next outing on Tuesday when fourth-ranked Baylor visits Manhattan.
Missouri (14-1, 1-1) was off to its best start since the 1981-82 squad opened with 19 wins. The Tigers led only once, at 3-2, and were thoroughly beaten in almost every aspect.
Marcus Denmon scored 17 points for Missouri and Michael Dixon added 16 in defeat.