Inter Milan lost 4-3 at Palermo, allowing four goals in a league match for the first time in seven years, and Juventus played the first official match in its $168 million stadium, opening its Serie A season with a 4-1 win over Parma on Sunday.
In Inter's first match since Samuel Eto'o transferred to Russian club Anzhi Makhachkala, new Inter coach Gian Piero Gasperini saw his team done in by a porous three-man defense.
Palermo captain Fabrizio Miccoli scored two goals, including one in the 86th minute that broke a 2-2 tie, and Abel Hernandez and Mauricio Pinilla scored for the hosts. Diego Milito scored twice for Inter and newly signed Diego Forlan got a goal in second-half injury time.
It was the first time Inter allowed four goals in the league since a 4-1 defeat to Roma in March 2004.
Juventus Stadium, a 40,200-seat venue, opened Thursday with an exhibition 1-1 tie against England's Notts County. On Sunday, midfielder Andrea Pirlo set up a goal for Stephan Lichtsteiner in the 16th minute and Simone Pepe doubled the lead in the 58th, converting a pass from captain Alessandro Del Piero.
Another new signing, Chilean Arturo Vidal, scored with a long shot in the 73rd, and Claudio Marchisio made it 4-0 in the 83rd after another setup from Pirlo, signed after a decade with AC Milan.
Parma scored on a penalty kick from Sebastian Giovinco in added time after Juventus defender Paolo De Ceglie was shown a red card.
Elsewhere, it was: Catania 0, Siena 0; Chievo Verona 2, Novara 2; Fiorentina 2, Bologna 0; Genoa 2, Atalanta 2; Lecce 0, Udinese 2; and Roma 1, Cagliari 2.
American midfielder Michael Bradley, acquired by Chievo from Germany's Borussia Moenchengladbach, was on the bench but didn't play.
Defending champion AC Milan drew 2-2 with Lazio on Friday and Napoli beat Cesena 3-1 Saturday.
BARCELONA, Spain (AP) — Ruben Castro's late goal gave Real Betis a 1-0 win over Mallorca, while Osasuna kept up its strong start to the Spanish league with a 2-1 victory over Sporting Gijon.
The Spanish striker was well-placed at the far post for his volley after a corner kick was unintentionally flicked on by a Mallorca defender in the 86th minute.
It was Castro's second late winner in as many weeks as Betis maintained its perfect start to the season, lifting the promoted club to the top of the league standings along with Real Madrid and Valencia. Defending champion Barcelona is two points behind.
Elsewhere, Levante couldn't take advantage of its extra man in the final 10 minutes after Racing Santander midfielder Papakouly Diop was sent off with two yellow cards and had to settle for a 0-0 away draw.
Zaragoza failed to bounce back from the 6-0 loss to Madrid in week one as it was held to a 0-0 draw by promoted Rayo Vallecano. Espanyol beat visiting Athletic Bilbao 2-1.
LONDON (AP) — West Bromwich Albion earned its first points of the season with a 1-0 victory over promoted Norwich, while Blackburn gained a 1-1 draw at Fulham.
Nigerian forward Peter Odemwingie pounced on a defensive error to clip home a third-minute goal at Carrow Road for West Brom, which ended a run of three straight losses.
Blackburn hung on for a draw at Craven Cottage after surrendering a lead given to the visitors by Ruben Rochina, who scored off the underside of the crossbar from the edge of the penalty area in the 32nd minute.
Bobby Zamora equalized five minutes later for Fulham, leaving both teams stuck in the bottom three. Blackburn remained bottom, however.
"We've got spirit, we've got togetherness. We didn't sit back and just defend, we came with quite an attacking threat," said Blackburn manager Steve Kean, who has come under fire from supporters after the team's sluggish start to the season.
American midfielder Clint Dempsey of Fulham and his teammates lined up with arms around each other's shoulders before their match to observe the 10th anniversary of the terrorist attacks on New York and Washington. Players from both teams wore black armbands on their left sleeves.
BERLIN (AP) — Mario Mandzukic scored twice as Wolfsburg came from behind to beat Schalke 2-1 in the Bundesliga.
Mandzukic canceled out Raul Gonzalez's 13th minute opener with a header in the 33rd, and the Croatian secured Wolfsburg's first win after three losses when he scored again in the 82nd.
"We invested more that Schalke did and fully deserved to win," said Wolfsburg coach Felix Magath, who was facing his previous club.
Schalke missed the chance to join Bayern Munich and Werder Bremen at the top of the standings.
Earlier, Timmy Simons scored two penalty kicks in four minutes to give Nuremberg a 2-1 win at Cologne.
In the second division, American forward Edson Buddle was injured in Ingolstadt's 4-1 defeat against Union Berlin and left the game after 14 minutes.
PARIS (AP) — Souleymane Camara scored on a curling shot in the 75th minutef to give Montpellier a 1-0 win over Nice and help his team retain one-point lead over second-place Lyon in the French league.
Also Sunday, Nancy drew 0-0 with Auxerre to remain in the relegation zone and Paris Saint-Germain defeated Brest 1-0 on Javier Pastore's 68th-minute goal.
AMSTERDAM (AP) — Feyenoord moved into fourth place in the Dutch league with a 3-1 win over struggling NAC Breda.
Otman Bakkal, Karim El Ahmadi and John Guidetti scored for Feyenoord after Robbert Schilder had netted the opener for NAC, which has yet to win this season.
PSV Eindhoven needed a late goal from Wilfred Bouma to earn a 3-3 draw at VVV Venlo, which had Marcel Meeuwis sent off in injury time. PSV took a comfortable lead from Ola Toivonen's and Dries Mertens' first-half goals before VVV hit back when Ferry de Regt, Uche Nwofor and Maya Yoshida each netted inside six minutes.
Also Sunday, SC Heerenveen secured its first win of the season with a 3-0 victory against FC Groningen.
LISBON, Portugal (AP) — American defender Oguchi Onyewu made his Portuguese league debut in Sporting Lisbon's 3-2 win at Pacos Ferreira.
Onyewu, acquired in the summer from AC Milan, played all 90 minutes in Saturday's game, his first competitive appearance for the club.