Sam Bradford's first pass of the night, the opening play of the game, resulted in an 83-yard touchdown to Brandon Gibson. His third pass was picked off by Alterraun Verner, but the Rams starting QB hung in and played the first half, finishing 8-of-15 for 138 yards.
Steven Jackson had six rushes for 10 yards for the Rams.
"It was the first live action I've had," Jackson said. "It's a great feeling to see where I'm at, see where I mesh up with the offensive line and with the scheme."
A.J. Feeley went 5-of-9 for 44 yards, including a 19-yard TD to Donnie Avery in the third quarter. Lewis misfired on just two of his 10 passes.
Titans starter Matt Hasselbeck connected on 7-of-9 passes for 74 yards, but had the wind knocked out of him with 5 1/2 minutes left in the second quarter. He was attended to by medical staff, but walked off the field under his own power.
Jake Locker replaced Hasselbeck and went 8-of-18 for 82 yards. Rookie Hamie Harper gained 83 yards on 11 carries and had a one-yard scoring run.