Natalie Novosel scored a career-high 27 points and No. 16 Notre Dame beat Gonzaga 70-61 on Wednesday night.
Skylar Diggins added 19 for Notre Dame (10-3).
Gonzaga led by two at the half and four midway through the second half before Novosel took over to help the Irish pull away for the victory.
The two teams combined for 44 turnovers and Notre Dame had to sit forward Devereaux Peters for much of the second half with foul trouble, but Novosel helped keep them in the game.
Peters came back in to convert a putback with six minutes remaining to give Notre Dame a 60-57 lead, and Novosel then drew contact while rolling in a layup for a three-point play that put the Fighting Irish up by six with just 5:08 to play.
Kayla Standish scored 16 points to lead the Bulldogs (10-4).