Kurt Busch, currently ninth in the standings driving with that team, is moving to the organization's No. 22 with sponsorship from Shell-Pennzoil, putting Keselowski in the Miller Lite-sponsored entry.
"We're extremely proud of our long-standing partnership with MillerCoors and are excited to extend this successful relationship," team owner Roger Penske said. "Brad is a tremendous talent with a bright future and I look forward to watching him continue the great tradition of the Blue Deuce."
Keselowski finished third in the Nationwide Series standings in both 2008 and 2009 before making his full-season Cup debut with Penske this year. He is currently second in the Nationwide standings and 25th in the Cup standings. He already has a Cup win to his credit, though, taking the victory at Talladega Superspeedway last fall while running a limited schedule.
"To follow champions like Rusty Wallace and Kurt Busch in the legendary Blue Deuce is a dream come true," Keselowski said. "The Miller Lite Racing team is accustomed to winning on and off the track, and I can't wait to do my part to build on that tradition."