Hillary Clinton once again delivered a hard-hitting speech on Donald Trump Tuesday, hammering his business record and even warning he would throw the economy back into recession if elected – to which Trump responded, “How can Hillary run the economy when she can't even send emails without putting entire nation at risk?”

Trump, who countered Clinton’s address Tuesday with a blizzard of Twitter comebacks, also announced he plans to deliver a more formal rebuttal on Wednesday.

Clinton spoke Tuesday in the vital swing state of Ohio. She echoed some of Mitt Romney’s criticism in a similar address earlier this year, mocking Trump for his record of corporate bankruptcy filings while saying his ideas for the economy “would be disastrous.”

Those hit the hardest by his plans, she said, would be the same Americans who faced the toughest fight to recover from the 2008 recession. Clinton added: "Just like he shouldn't have his finger on the button, he shouldn't have his hands on our economy."

Her speech included stinging one-liners, including: "He's written a lot of books about business. But they all seem to end at chapter 11." 

Throughout the speech, Trump fired back on Twitter, questioning Clinton's fitness for office by invoking everything from her personal email scandal to her immigration policies to her family foundation's fundraising. 

Trump had originally planned to deliver an anti-Clinton address last week but changed the focus of those remarks to national security and terror in the wake of the Orlando attack. He now plans that address for Wednesday. 

In her speech, Clinton used Trump's own statements to undercut his economic credentials, pointing to remarks he made that that U.S. could sell off assets, default on its debt and that wages are too high. She also repeated a comment he made that pregnant employees are an "inconvenience."

The Associated Press contributed to this report.