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The state of Florida refuses to let the infestation of Burmese pythons in the Everglades slither out of its grip, and has hired a select team of 25 hunters to deal with the issue.

And apparently the effort is paying off.

On Tuesday, they celebrated the 1,000th python capture in a little over a year — an 11-foot-two-inch male snake.

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Python hunter Brian Hargrove, right, is helped by Marcos Fernandez, left, with the South Florida Water Management District, as they measure and weigh the 1,000th python caught in the Florida Everglades. (AP)

The South Florida Water Management District (SFWMD) program began in March 2017, as the non-native, giant constrictor snakes have eliminated 99 percent of the Everglades’ indigenous mammals, the Associated Press reports.

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Marcos Fernandez, with the South Florida Water Management District, holds the head of a python before measuring and weighing it. (AP)

"Getting it out of there was a good feeling," said hunter Brian Hargrove, who has been crowned as the program’s “most prolific” hunter, having captured and killed over 110 pythons in the past 15 months. Hargrove said he first hated having to kill the pythons, but wants to help save wildlife in the besieged Everglades.

"I like to hunt with a friend because if we are successful, I don't like to have put an animal down. It's a beautiful creature. It's not their fault," Hargrove mused. "But it's the job."

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Python hunter Brian Hargrove, right, is paid a bounty by Terry Fitch, left, with the South Florida Water Management District, after they measured and weighed the 1,000th python caught in the Florida Everglades. (AP)

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Python hunter Dusty Crum carries a python caught in the Florida Everglades before having it weighed and measured, Tuesday, May 22, 2018, in Homestead, Fla. (AP)

Burmese pythons have been abandoned in the Everglades by owners for decades, resulting in an unanticipated population boom, with females laying between 50 and 100 eggs at once, Orlando Weekly reports.

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Python hunter Dusty Crum cuts open a female python caught by fellow hunter Isaiah Figurereo, after it was measured and weighed, Tuesday, May 22, 2018, in Homestead, Fla. The 12-foot-plus long snake contained 34 eggs. (AP)

Initially restricted to Miami-Dade County, the SWFMD program has been expanded into Broward and Collier counties.

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Marcos Fernandez, left foreground, with the South Florida Water Management District, measures and weighs a python caught in the Florida Everglades, Tuesday, May 22, 2018, in Homestead, Fla. (AP)

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"We've removed potentially tens of thousands, if you consider their reproductive abilities," Mike Kirkland, SFWMD project manager, told AP. "The more they eat, the bigger they get.”

Hunters are paid $8.10 an hour, plus bonuses for extra-large captures, the Weekly reports.

The pythons have averaged around 9 feet in length, though hunters also have brought in 14-inch hatchlings as well as snakes nearly 18 feet long.

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The Associated Press contributed to this report.