"Sopranos" star Drea De Matteo is one of many New Yorkers who lost an apartment in an East Village explosion Thursday.

The 43-year-old actress posted pictures of the building up in flames from across the street.

"A hole where my NYC home of the last 22 years once stood..." she captioned a photo she took of the scene.

A hole where my NYC home of the last 22 years once stood... RIP 123 2nd Avenue ������

A photo posted by Drea De Matteo (@dreadematteo) on

The powerful blast caused the collapse of three buildings and fire damage to a fourth, the NYC fire department said. Nineteen people were injured, four critically after the powerful blast and fire sent flames soaring and debris flying on Thursday.

Preliminary evidence suggested a gas explosion amid plumbing and gas work inside the building was to blame.

"Modern Family" star Sarah Hyland also tweeted about her connection to the buildings.

The Associated Press contributed to this report.