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Syrian security forces stormed dormitories at Aleppo University to break up anti-government protests, killing at least four students and wounding several others in an hourslong rampage that ended Thursday morning and left part of the campus in flames, activists and opposition groups said.

They said the main university in Syria's largest city shut down in the wake of the violence, but it was not clear for how long.

Around 1,500 students had been protesting in student quarters next to the main campus late Wednesday when security forces and pro-regime gunmen swept into their residences, firing tear gas at first, then live ammunition to disperse them.

The raid followed an attack on the protesters by pro-regime students armed with knives, activists said.

Student activist Thaer al-Ahmed said panic and chaos ensued as students tried to flee.

"Some students ran to their rooms to take cover but they were followed to their rooms, beaten up and arrested," he said. "Others suffered cuts and broken bones as they tried to flee."

Raids and intermittent gunfire continued for about five hours through early Thursday, he said, adding that dozens of people were wounded, some critically, and around 50 students were arrested at the state-run university.

Aleppo, a major economic hub, has a population that has remained largely loyal to President Bashar Assad and has been largely spared from the violence that has plagued other Syrian cities.

But university students — many from rebellious areas such as the northern Idlib province — have been staging almost daily protests calling for the fall of Assad's regime. Al-Thaer, a law student, said the campus and dormitories have been raided before, but Thursday's raid was the most violent.

The student quarters — known as the University City — comprise 20 dormitories that house more than 5,000 students next to the university campus. Students there often shouted out anti-Assad slogans from their rooms at night, al-Thaer said.

An amateur videos showed a large number of security forces apparently storming the dorms Wednesday night. Another showed a students protest earlier Wednesday, during which protesters shouted: "We don't want you, Bashar!"

A video posted on Thursday showed the university campus with its windows shattered and a man dousing a smoldering fire with a bucket of water.

The authenticity of the videos could not be confirmed.

The university was founded in 1958. The school's website has a picture of Assad with the words: "I Believe in Syria."

The Local Coordination Committees activist group said five students were killed and some 200 arrested in the raids, while the British-based Syrian Observatory for Human Rights put the death toll at four. The Syrian government has prevented independent reporting in the country, making it impossible to independently verify casualty figures.

"Regime forces demanded through loudspeakers that the dorms be evacuated, then began detaining the students," the LCC said in a statement.

Al-Ahmed and the Observatory's director Rami Abdul-Rahman said pro-regime students armed with knives tried to break up the protest before the security forces raided the dorms.

Syria's persistent bloodshed has tarnished efforts by a U.N. team of observers to salvage a truce brokered by U.N. special envoy Kofi Annan that started to unravel almost as soon as it was supposed to begin on April 12.

The two sides have blamed each other for thwarting the truce, with Assad's forces trying to repress demonstrators calling for him to step down and an armed rebellion that has sprung up as peaceful protests have proved ineffective against his forces. The U.N. says 9,000 people have died since the uprising began in March 2011.

Syria's state-run news agency SANA said Wednesday that gunmen had assassinated Ismail Haidar, the son of the Syrian Social Nationalist Party's leader. Haidar was shot dead by "terrorists" on the highway from Homs to Misyaf, it said. Haidar's father is also a member of the Popular Front for Change and Liberation, which calls for peaceful, democratic change in Syria but is considered by some to be close to the regime.

The Observatory also said that Bassel Raya, a former basketball player who played on the Syrian national team, died Thursday from wounds suffered last week when he was shot by gunmen in a Damascus suburb.

Despite the violence, the international community still sees the peace plan as the last chance to prevent Syria from falling into civil war — in part because no country wants to intervene militarily.

The head of the U.N. observers, Norwegian Maj. Gen. Robert Mood, visited the central cities of Homs and Hama, where anti-regime sentiment runs high, on Thursday.

He said there is still "a good chance and an opportunity" to break the cycle of violence.

Reporters accompanying the observers Thursday on the tour interviewed residents who said life was fairly normal during the day but was worrisome at night.

"The situation is calm during the day but scary at night," said Maher Jerjous, a 53-year-old resident of the Bab al-Quba district in Hama. "Masked gunmen ... roam the streets. There are kidnappings on public roads. You will not see anyone (on the streets) after six."

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Associated Press writer Albert Aji contributed to this report from Homs and Hama, Syria.