There were no early indications of injuries or fatalities from the twister that struck the south side of Sioux Falls around 11:40 p.m., the Argus Leader reported.
Nearly 13,000 utility customers were left without electricity, Xcel Energy reported, according to the newspaper.
A flash flood warning remained in effect for the area while the tornado moved on to Minnesota and Iowa, the report said.
The newspaper reported via Twitter that Avera Heart Hospital lost parts of its roof and some patients “need attention.”
A Best Buy store and other businesses also suffered roof damage, social media posts said.
This is a developing story. Check back for updates.