On the heels of weeks of deadly storm systems, the National Weather Service (NWS) said Saturday that a strengthening "low pressure and frontal" system is expected to move across the Central Plains toward the Ohio Valley.
Over the last few weeks, tornadoes and baseball-sized hail have torn through the South and Gulf Coast, killing several people, forcing water rescues, knocking out power for hundreds of thousands and destroying vehicles, homes and businesses.
On Sunday, the cold front associated with the system is predicted to move southward, bringing Slight Risks of severe weather into the Mid-South.
Moderate to heavy rainfall is reportedly also a concern across the Ohio Valley on Sunday.
Freeze Warnings and Frost Advisories are in effect on Saturday for parts of the Ohio Valley and Upper Great Lakes region, with lows in the 30s.
Temperatures will also be "well below normal" across the northern tier states and most of the eastern U.S. before a warm-up in the Southeast to Carolinas on Sunday.
To the west, snow is forecast in the Northern and Central Rockies over the next two days and around a foot of snow could accumulate in the highest elevations through Monday morning.
Some late-season snow is also possible in the Northern High Plains, with potential accumulations of one or two inches.
Across the south-central U.S. and parts of the High Plains, temperatures are rising into the 90s and South Texas will see temperatures in the 100s.