Milwaukee, WI – Ryan Braun hit the winning home run in the 1, in the game set.
Braun led off the inning after Kameron Loe (4-7) held the Rockies off the board in the top half. He worked the count full against Matt Lindstrom (2-2) before sending the 10th pitch of the at-bat over the fence in left-center.
"You fall behind a good hitter like that and eventually you're gonna pay for it," said Lindstrom. "The ball just came back over the middle and he made me pay for it."
Prince Fielder added a homer for the Brewers, who defeated the Phillies on Sunday to halt a five-game skid. They remain 6 1/2 games ahead of the Cardinals in the NL Central.
"We didn't do much offensively, so a couple of big at-bats," said Brewers manager Ron Roenicke.
Wilin Rosario had an RBI double for the Rockies.
Loe allowed runners to reach second and third with two down in the top of the 11th, but Rosario grounded out weakly to second.
Both teams squandered opportunities early.
The Rockies placed runners at the corners in the first, but Mark Ellis was cut down at the plate on a Troy Tulowitzki grounder. With the bases loaded in the third, Ellis was thrown out at the plate to end the inning.
Colorado took a 1-0 lead in the fourth on doubles by Seth Smith and Rosario.
Fielder was stranded after a leadoff double in the home half, but tied the game with a one-out blast to straightaway center in the sixth, his first home run since September 2.
"At this time of year, it doesn't matter how you look, as long as you win," said Braun.
Braun was 0-for-4 with a strikeout before his final at bat...The Brewers are 52-22 at home this season, which marks the best home record in the majors. Their 3-2 victory over Philadelphia on Sunday snapped a season-high six-game losing streak at Miller Park...The Cardinals defeated the Pirates 6-4 on Tuesday...Tulowitzki left the game with a sore left hip. He sat out Sunday's 4-1 win over Cincinnati with the same ailment.