Gunfire erupted in Kabul Friday after a large explosion in a heavily protected area close to foreign embassies and government buildings.
Initial police reports suggested three attackers targeted a guest house attached to the Spanish embassy, according to Reuters.
Interior Ministry spokesman Sediq Sediqqi said the explosion appeared to have come from a car bomb.
There were no immediate details of damage or casualties, Reuters reports. Security officials cordoned off the surrounding streets as ambulances rushed to the scene, according to The Telegraph.
Police said gunfire had broken out following the blast, which came after Afghan President Ashraf Ghani returned to Kabul from a regional peace conference in Islamabad aimed at reviving peace talks with Taliban militants.
Days earlier, the Taliban attacked Kandahar Air Field, killing 50 people, mainly civilians.