Mexico's interior ministry says it has distributed 100,000 photographs of drug lord Joaquin "El Chapo" Guzman to highway toll booths around the country since his weekend escape from a maximum security prison.

In a statement Wednesday, the ministry outlined actions taken in search of Guzman:

It says 10,000 agents of various components of the federal police remain on high alert across Mexico and authorities have established 101 checkpoints on major highways throughout the country

Hospitals, hotels and funeral homes are being checked. Forty-eight canine teams are searching passenger and cargo vehicles. Airports are on alert, closely reviewing passengers on private planes.

Guzman is once again Mexico's most wanted criminal since he escaped late Saturday through a mile-long tunnel dug to come up under the shower of his prison cell.