Updated

An explosion has shaken the center of the eastern Ukrainian city of Donetsk, where pro-Russian separatists have taken over a regional administration building.

An AP reporter nearby heard the explosion and arrived to see a van in flames in front of the building. He saw three injured people being taken away.

The breakaway Donetsk People's Republic said on its Twitter feed that the van was used by one of the group's leaders, Denis Pushilin, but said he was not in the vehicle.

The same tweet said four people were injured and one was in grave condition.