Updated

Egypt's Muslim Brotherhood is staging an anti-Israel rally in Cairo to protest Israeli airstrikes in Syria and the detention of a Muslim cleric.

Chants of "the people want destruction of Israel" rang out Friday inside Al-Azhar mosque, the centuries-old seat of Sunni Muslim learning.

The rally is the first such protest by the Brotherhood, from which Egyptian President Mohammed Morsi hails, since it gained prominence after 2011 uprising that ousted president Hosni Mubarak.

Group officials say they are protesting the Israeli detention of top Palestinian Muslim cleric in the Holy Land in a rare crackdown on a leading religious figure that drew fierce condemnation from Palestinians. The demonstrators also were denouncing Israeli airstrikes in Syria that targeted alleged shipments of advanced Iranian missiles thought to be bound for Hezbollah.