Trevor Booker had 15 points and 11 rebounds to help No. 19 Clemson win its 30th straight game in November, 102-66 over Winthrop on Monday night.
The Tigers (4-0) haven't lost in college basketball's opening month since a 79-70 defeat at future Atlantic Coast Conference member Boston College on Nov. 26, 2004.
It's a streak Booker and the Tigers easily increased against overmatched Winthrop (2-2).
Booker, Clemson's 6-foot-7 senior, had a three-point play and fadeaway jumper as the Tigers broke on top 12-4 less than 4 minutes in. He really cranked it up to start the second half with six points in a 15-0 run that turned Clemson's comfortable margin into a blowout.
Booker had his second double-double this season and the 24th of his career.
After a first half slowed by a total of 30 fouls, the Tigers showed their flash to start the final 20 minutes.
Booker and Tanner Smith had baskets and David Potter hit a 3. Smith stole the ball on Winthrop's next possession, feeding a wide-open Booker for a left-handed jam that brought down the house.
Booker closed the spurt with a driving scoop shot that put the Tigers up 65-32. Clemson coach Oliver Purnell applauded his team when the Eagles called a timeout to try and cool off the run.
Six Tigers scored in double figures. Potter, Noel Johnson and Andre Young had 12 points each, Jerai Grant had 11 and Smith 10.
The Eagles' frustration showed. George Valentine was called for a first-half technical for an elbow to the face of Smith that left a bright, red mark. Winthrop coach Randy Peele later drew a technical as he complained to an official.
The only drama down the stretch was if Clemson would top the 100-point mark for the first time since Dec. 23, 2006, when it beat Western Carolina 103-60.
Walk-on Jonah Baize hit a 3-pointer to give the Tigers 99 points with 1:06 left, then followed with another long-distance shot from the right corner with 11.5 seconds to go.
Justin Burton had 13 points for the Eagles, who committed 26 turnovers.
The Tigers might have a difficult time maintaining their November success. They will play in the 76 Classic in Anaheim, Calif., an eight-team event that features ranked teams Minnesota, Butler and West Virginia.They open against Texas A&M on Thursday.
The Eagles won in their last visit to Littlejohn Coliseum in 2001. That's when Winthrop was flying high as a Big South Conference power with eight NCAA tournament appearances between 1999 and 2008.
These Eagles went 11-19 in 2008-09 _ their first losing season since 1997-98.
Grant, the 6-foot-8 son of former Oklahoma standout Harvey and nephew of Tiger great Horace, took control of the inside with two dunks and two blocks.
Grant had a rebound dunk of a missed jumper by Demontez Stitt to put Clemson ahead 42-27.