A storm will spread a swath of accumulating snow and slippery travel from the central Plains to the southern Appalachians and part of the Atlantic coast this weekend.
Because of the time of the year, where the ground is beginning to warm and the sun is getting stronger, snow will struggle to accumulate on roads and sidewalks during the day.
However, especially where heavy snow falls at night, paved surfaces can become slippery even into areas well to the south. Roads in the higher elevations, bridges, overpasses and areas shaded from the sun during the day will be most prone to becoming slushy.
Aircraft deicing operations can lead to flight delays at some of the hubs from the Plains to the interior South.
Snow will sweep from Nebraska to Missouri during Friday night and Saturday morning, after blanketing portions of Montana and the Dakotas on Friday.
Motorists should anticipate slushy conditions along portions of Interstate 70 from Kansas City, Missouri, to near St. Louis by Saturday morning.
On Saturday, a few inches of snow can accumulate, mainly on non-paved surfaces in the Ozarks over southern Missouri and northern Arkansas. Rain or a wintry mix will end as snow near the Mississippi River.
"During Saturday night, the swath of snow will continue to progress eastward. A couple of inches of snow can accumulate around Nashville, Tennessee, with several inches possible over the mountains in eastern Tennessee and western North Carolina," according to AccuWeather Senior Meteorologist Henry Margusity.
Among the southern cities that could pick up enough snow to shovel and plow include Knoxville and Bristol, Tennessee, and Asheville, North Carolina.
Motorists should be prepared for slush an snow on the roads along I-26, I-40, I-77 and I-81 in the southern Appalachians and the foothill and Piedmont areas during Saturday night.
Rain will change to snow or end as a wintry mix along the northern counties of Mississippi, Alabama and Georgia from Saturday night to Sunday morning.
Farther to the east, areas from upstate South Carolina and central North Carolina to part of the Outer Banks, a period of snow or rain changing to snow will occur on Sunday.
Accumulating snow will be mostly limited to non-paved surfaces around Charlotte, Raleigh and Elizabeth City, North Carolina.
Wet travel is forecast from Jackson, Mississippi, to Birmingham, Alabama; Atlanta; Columbia, South Carolina; and Fayetteville, North Carolina.
Farther south, thunderstorms can be locally heavy and gusty in parts of Texas and the I-10 corridor this weekend.
Ahead of and in the wake of the storm, a freeze will threaten blossoms and nursery stock from Kansas and Missouri to the Carolinas and Virginia this weekend.
Another snowstorm will threaten areas farther to the north in the Midwest by Monday. The storm could evolve into a major nor'easter for the mid-Atlantic and New England states by Tuesday.