Gusty winds and snow will sweep across the north-central United States from Monday night to Tuesday night.
The combination of the snow and wind could lead to possible white-out conditions from South Dakota into neighboring Nebraska and Minnesota.
Travelers along interstates 29, 35 and 90 should be prepared for treacherous driving conditions.
A storm will emerge from the Rockies and ride along the leading edge of a fresh wave of cold air.
“Periods of snow will begin across parts of northern Nebraska and South Dakota late Monday night,” AccuWeather Meteorologist Kevin Gilmore said. “Snow will increase in intensity during the daytime hours on Tuesday with gusty winds developing.”
“Wind gusts in excess of 20 to 30 mph will cause localized blizzard conditions with blowing and drifting snow,” he added.
Snow will overspread portions of Wisconsin and the Upper Peninsula of Michigan late on Tuesday.
The area at greatest risk for significant snowfall accumulations will stretch from South Dakota into northern Nebraska, northwestern Iowa and southern Minnesota.
Along this swath, a widespread 3 to 6 inches of snow will fall, with higher amounts up to a foot possible.
Snow will overtake Minneapolis and St. Paul during the afternoon on Tuesday and intensify during the evening hours. Commuters to and from the city should be prepared for slippery and snow-covered roadways during Tuesday evening.
Be prepared for impacts to travel, according to Gilmore.
There will be a sharp variation in snow totals to the north, where dry air can limit snowfall, and to the south, where rain may mix in and limit accumulation.
Chicago will remain far enough south to receive mostly rain from the storm. Snow can mix in on the back edge of the storm as the cold air plunges southward.
The weather will turn more tranquil from Wednesday to Thursday with just a few lingering snow showers and flurries expected across the region.