Several days of dangerous thunderstorms will threaten millions from the midwestern United States to the Great Lakes through late week.
Residents and travelers across the region will want to monitor the weather situation over the next few days.
The threat for violent storms will gradually shift from the Midwest to the Great Lakes from Wednesday to Friday.
Each day through Friday will feature a threat zone where thunderstorms could produce damaging wind gusts, large hail and torrential downpours. A few of the strongest storms could spin up a tornado or two.
The multi-day threat for severe weather can be attributed to several systems riding along the northern tier of the U.S., according to AccuWeather Senior Meteorologist Alex Sosnowski.
Storms will likely be most active during the late afternoon and evening hours.
Individual storms that form during the afternoon can merge into larger thunderstorm complexes, which can produce violent weather well into the overnight and early morning hours.
Areas that experience residual clouds and thunderstorms during the morning may be spared by the worst of the severe weather in the afternoon.
The first round in this next string of severe weather will occur on Wednesday, when violent storms will focus on portions of South Dakota, Nebraska, Minnesota and Iowa.
Storms are expected to come to life near or just east of the Black Hills, before racing eastward during the evening hours. A few strong storms could skirt northern Kansas.
"The precedent for stronger storms will continue on Thursday and Friday," according to AccuWeather Senior Meteorologist Matt Rinde.
"The next round will move through Minnesota and Iowa on Thursday before shifting eastward through Wisconsin and Illinois Thursday night," he added.
Strong thunderstorm wind gusts capable of damage to trees and power lines could target cities such as Omaha, Nebraska; Kansas City, Missouri; Minneapolis; Des Moines, Iowa; Madison, Wisconsin; and Chicago.
Flash and urban flooding will be possible, especially in locations that have already been hit by heavy storms one or more times this week.
Travel could become treacherous on portions of interstates 29, 35, 80 and 90 for a time.
On Friday, areas from the Great Lakes to the lower Ohio Valley could face the threat for storms to re-fire and become severe. Isolated severe storms could extend as far west as the mid-Mississippi Valley.
Residents of Indianapolis, Detroit, Cleveland, Cincinnati, Pittsburgh and the surrounding communities should be on alert for locally damaging thunderstorms during the late afternoon and evening hours. Severe storms could stretch as far north as Toronto.
The exact timing and extent of severe weather will be refined as Friday approaches.