Severe thunderstorms packing damaging wind gusts, hail and torrential downpours were pushing eastward late Wednesday, aiming for the central and northern Appalachians.
The storms pose a significant risk to lives and property. A few of the strongest storms could also bring a tornado.
Some communities can be hit with power outages and road closures with wind gusts in excess of 60 mph and 2 inches of rain in an hour's time.
States impacted by the storms into Wednesday night include, Ohio, Pennsylvania, New York, West Virginia, Kentucky, Maryland, Virginia and Tennessee.
UPDATES: (All times are listed in EDT)
4:16 p.m. EDT Wednesday: Wind gusted to 71 mph at Port Columbus Airport, Ohio, recorded by NWS.
4:10 p.m. EDT Wednesday: A train was derailed by thunderstorm winds in Melbern, Ohio, southwest of Toledo, reported the emergency manager. Multiple power lines and trees also downed.
3:46 p.m. EDT Wednesday: Mesonet recorded a thunderstorm wind gust of 86 mph, northwest of Columbus, Ohio, in St. Marys.
2:35 p.m. EDT Wednesday: Possible tornado developing near Cleveland, Ohio.
2:19 p.m. EDT Wednesday: Trained spotter reported rotating wall cloud in Bedford Heights, Ohio.