A narrow band of heavy snow will drop up to a foot of accumulation on parts of Iowa, Minnesota, Wisconsin and Michigan through Monday.
Snow has already dropped between 2 and 4 inches on Omaha and Lincoln, Nebraska this morning.
This band of snow will continue to expand north eastward into tonight, bringing significant snow accumulations to Des Moines, Mason City, Waterloo, La Crosse, Wausau and Marquette.
Snowfall rates this evening and tonight will approach one inch per hour from northeast Iowa through central Wisconsin, including in the cities of La Crosse and Eau Claire.
This heaviest band of snow will shift into the Upper Peninsula of Michigan after midnight tonight into Monday morning, bringing heavy snow to Marquette.
While this storm is only expected to produce a narrow swath of snow, residents and travelers will run into significant slow downs on I-80, I-94, I-90 and I-35.
Snowfall totals will average 6-12 inches from near Des Moines through Waterloo, Iowa up to La Crosse and Wausau, Wisc., and throughout much of the U.P. of Michigan.
Outside of that zone, 3-6 inches of accumulation will be common through Monday for Rochester, Minn., along with Eau Claire and Madison, Wisc.
A few inches could accumulate in the southern suburbs of Minneapolis, Minn., though the heaviest snow will stay just to the south of there.
For a larger version of the snow map and more information on any winter weather watches or warnings in effect, click over to the AccuWeather.com Winter Weather Center.