Jennifer Kesse was last seen alive on Jan. 23, 2006, in Orlando, Fla. No one has seen or heard from her since, and no suspects have been identified in her disappearance.
Security footage shows a person parking Jennifer Kesse's black Chevy Malibu at an Orlando apartment complex about a mile from where she lived. The suspect – who appears to be 5”3 to 5”5 – has never been identified.
The largest missing person search in Oregon's history was launched for Kyron Horman, an 8-year-old Portland-area boy who disappeared June 4, 2010. Family members have said they believe the boy's stepmother, Terri Moulton Horman, had a role in his disappearance. To date, no arrests have been made in the case.
Natalee Holloway, an 18-year-old honor student from Mountain Brook, Ala., disappeared in May 2005 while on a high school trip to Aruba. Her remains have never been found. Joran van der Sloot, a Dutch national and the last known person to see Holloway alive, has given many different accounts of what happened to her. Van der Sloot remains imprisoned in Peru, charged with killing a 20-year-old Peruvian woman in May 2010.
Arizona rancher Robert Krentz was shot to death March 27, 2010, on his 35,000-acre ranch. Investigators were able to trace a single pair of foot tracks south to the U.S.-Mexico border. No suspects have been arrested in the case, but authorities believe a drug smuggler is likely responsible.
7-year-old Alexander, 5-year-old Tanner and 9-year-old Andrew Skelton of Morenci, Mich., disappeared on Nov. 25, 2010. The brothers were last seen on Thanksgiving day playing in the backyard of their father's home. Authorities said that statements made by their father, John Skelton, indicate that it's unlikely the boys will be found alive. Skelton has been charged with parental kidnapping, though no murder charges have been filed yet.
David Hartley, 30, of Milliken, Colo., was shot and killed Sept. 30, 2010, while jet-skiing with his wife, Tiffany, on Lake Falcon, a 25-mile-long lake along the U.S.-Mexico border. U.S. and Mexican authorities say the Hartleys encountered members of the Zeta drug cartel who shot at them as they fled on their jet skis. Hartley's body has never been recovered.
Zahra Baker, a 10-year-old cancer survivor from Hickory, N.C., was reported missing by her father, Adam Baker, on Oct. 9. The girl's dismembered body was found in different locations several weeks later. Elisa Baker, Zahra's stepmother, gave information to authorities that led them to her remains. Police also learned that Zahra may have been raped and beaten by two North Carolina men, though both have denied any wrongdoing. Elisa Baker is being held on an obstruction of justice charge relating to the girl's disappearance, but murder charges have not been filed yet.
Haleigh Cummings disappeared from her father's mobile home in Satsuma, Fla., in February 2009. Her father's 17-year-old live-in girlfriend, Misty Croslin, told police that she woke up to find the child gone and a back door propped open with a brick. Police say they don't believe the 5-year-old was snatched by a stranger, and Croslin is currently being held on unrelated drug charges. To date, no one has been charged in Haleigh's disappearance.
Stacy Peterson, of Bolingbrook, Ill., disappeared on Oct. 28, 2007. The woman's husband, Drew Peterson, told police that she called him to say she had left with another man and had abandoned her car at a nearby airport. Authorities launched an extensive search for Stacy -- Peterson's fourth wife -- but yielded no clues. On May 7, 2009, Drew Peterson, a former police sergeant, was charged with murdering his third wife, Kathleen Savio, who died in 2004 in what was first thought to be an accidental drowning. He has not yet been charged in the disappearance of Stacy Peterson.
The famed Hollywood publicist was shot to death inside her Mercedes Benz while driving home from a movie premiere last month. Law enforcement sources originally believed the murder was the work of a professional hitman, but later announced that ex-con Harold Martin Smith killed Chasen during a botched robbery. When investigators tried to question Martin in the lobby of his Los Angeles apartment building, he shot and killed himself. The gun used in the suicide is the same weapon that killed Chasen, cops said. Many in Hollywood, however, remain unconvinced that the killing was not a professional job.
Their stories have stumped investigators, agonized families and captivated the American public. Following are the names of some of the highest-profile crime victims whose cases remain unsolved to this day.