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The Latest: State police: 1 northbound lane of Arkansas interstate opened after crashes kill 3

The latest on a multi-vehicle crash that shut down Interstate 49 in southwest Arkansas (all times local):

2 p.m.

Arkansas State Police say one northbound lane of Interstate 49 has been reopened following chain-reaction crashes in both directions that killed three people and injured seven more.

The northbound lane reopened shortly before 1:30 p.m. Tuesday after both southbound lanes were reopened shortly before 11 a.m. One northbound lane where cleanup crews are working remains closed.

Police say the first collision happened at about 11:45 p.m. Monday near Fouke, about 160 miles southwest of Little Rock, when a tractor-trailer traveling south slowed down and was rear-ended. Ten vehicles were involved in this crash.

At about the same time, three tractor-trailers in the northbound lanes collided directly across the median from the southbound crash scene. State police say one of the trucks was carrying glue that spilled onto the highway.

State police say troopers are investigating whether fog may have contributed to the crashes.

11 a.m.

Arkansas State Police say southbound lanes of Interstate 49 have reopened following chain-reaction crashes in both directions that killed three people and injured seven more.

Police say the northbound lanes remained closed late Tuesday morning.

Police say the first collision happened at about 11:45 p.m. Monday near Fouke, about 160 miles southwest of Little Rock, when a tractor-trailer traveling south slowed down and was rear-ended. Ten vehicles were involved in this crash.

At about the same time, three tractor-trailers in the northbound lanes collided directly across the median from the southbound crash scene. State police say one of the trucks was carrying glue that spilled onto the highway.

State police say troopers are investigating whether fog may have contributed to the crashes.

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7:10 a.m.

Arkansas State Police say three people were killed and at least seven were injured in separate chain-reaction crashes on Interstate 49.

State police say the first collision happened at about 11:45 p.m. Monday when a tractor-trailer slowed down and was rear-ended. A total of 10 vehicles were involved in this wreck in the southbound lanes of traffic.

At about the same time, three tractor-trailers in the northbound lanes collided directly across the median from the southbound crash scene. State police say one of the trucks was carrying glue that spilled onto the highway.

State police say troopers are investigating whether fog may have contributed to the crashes.

Interstate 49 remains closed.

The wrecks happened near the town of Fouke, about 160 miles southwest of Little Rock.

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6:50 a.m.

Video from the scene of a major crash on an interstate in southwest Arkansas shows wrecks in both northbound and southbound lanes that are separated by a barrier.

Video from Shreveport, Louisiana, television station KSLA shows wrecked tractor-trailers, cars and trucks blocking Interstate 49 at Fouke, 9 miles south of Texarkana, early Tuesday.

The station reports that the first wreck happened in the southbound lanes and that the second wreck may have been caused by drivers in the northbound lanes looking at the other crash, but the causes of both crashes remain under investigation.

Arkansas State Police say there are an "unconfirmed number of fatalities" in the wrecks.

The National Weather Service says conditions were clear and dry at the time of the crash, though dense fog has since blanketed the area.

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5:55 a.m.

Interstate 49 is shut down near Texarkana after an early morning crash involving multiple vehicles. Arkansas State Police say there are initial reports of fatalities but details are still being confirmed.

State police say the crash happened shortly after midnight Tuesday about 9 miles south of Texarkana near the state's borders with Texas and Louisiana. Traffic is being re-rerouted near Fouke along U.S. 71.

State police say initial reports indicate "an unconfirmed number of fatalities" and injuries at the crash scene.

The crash happened in an area about 160 miles southwest of Little Rock.