The holes are positioned near petrol stations and motels along the mostly deserted and featureless highway.
Few people bother to stop unless they have to; tourism officials hope there are now 18 more reasons to do so.
Click here for more from the Nullarbor Links website
But if you like to play your golf on carefully-manicured greens and pristine fairways, this course is not for you.
There is hardly any grass, just dirt and stones. The greens and tees are artificial, and some aren't even green. Because of a lack of water for irrigation, some putting surfaces are made from sand mixed with diesel.
Alfie Caputo, the course's project manager, acknowledges it's hardly in pristine condition.
He says the world is full of courses like that, but his is different.
"I think people are looking for an adventure, and an experience," he said.Click here to continue reading this story from Sky News