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Sunburn Offers Clues for Pain Drug Development

Scientists have found a molecule in the body which controls sensitivity to pain from UVB irradiation, or sunburn, and say it may help them develop new drugs to treat pain in other common conditions such as arthritis .The CXCL5 molecule is part of a family of proteins called chemokines which recruit inflammatory immune cells to injured tissue, triggering pain and tenderness, the researchers said in a study in the journal Science Translational Medicine."We've identified this chemokine as an important factor that drives some forms of pain, and we did that in the context of UVB irradiation or sunburn," said Stephen McMahon from the Wolfson Centre for age-related diseases at King's College London and head of a research group called the London Pain Consortium."But this study isn't just about sunburn. More broadly we have identified a mediator that may be important in a variety of different pains states—particularly those associated with inflammation—and there are lots of those out there, for...

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  1. Sunscreen Ratings Still Misleading Despite New SPF Labels, Consumer Group Says

    The new sunscreen labels hitting store shelves this summer may be designed to make the products more effective and easier to use but according to a consumer watchdog...

  2. Heading to the beach? New SPF regulations issued by the FDA

    In the summer of 2011, Andrea Syglowski noticed a mole she’d had her entire life was starting to look different. Concerned, she booked an appointment with a dermatol...

  3. 5 factors that raise your skin cancer risk

    More reason to do regular skin checks: Melanoma rates in young women have skyrocketed. A Mayo Clinic study finds they've increased eightfold between 1970 and 2009. (...

  4. The golden rules of sun protection

    Unless you've been living under a rock, you know to apply sunscreen. There's a lifesaving reason to: About 3.5 million cases of skin cancer will be diagnosed this ye...

  5. Summer sun safety: Contact lenses with UV protection

    With the official arrival of summer, taking protective measures against the sun’s dangerous rays is essential. While many may think they’re prepared with sunscreen, ...

  6. How to make your spray tan last

    If you want a golden glow this summer without damaging your skin or putting yourself at risk for skin cancer, consider a spray tan. It's an easy, quick way to get so...

  7. Daily Sunscreen Use Slows Skin Aging

    Get burned or get younger.New research provides some of the strongest evidence to date that near-daily sunscreen use can slow the aging of your skin.Ultraviolet rays...

  8. 9 common skin problems and solutions

    As the body's protective outer-shell, your skin puts up with a lot. Harmful elements such as chemicals, infections, cuts, scrapes, and sunlight keep the seemingly de...

  9. FDA calls for cancer warnings at indoor tanning salons

    Indoor tanning beds would come with new warnings about the risk of cancer and be subject to more stringent federal oversight under a proposal unveiled Monday by the ...

  10. FDA Wants Cancer Warning On Tanning Beds, Closer Supervision

    Like cigarettes, tanning beds may get a warning.Indoor tanning beds would come with new warnings about the risk of cancer and be subject to more stringent federal ov...

  11. 8 medication mistakes moms make—and how to avoid them

    You want the best for your children, but sometimes the health decisions you make can be dangerous. Read on for some of the most common medication mistakes moms make ...

  12. Surprising health uses for everyday foods

    Vinegar http://global.fncstatic.com/static/managed/img/fn2/travel/Apple%20Cider%20Vinegar%20and%20Apple%20Juice.jpgUse it to: Soothe a sunburnSoak a cotton ball in a...

  1. Science Seeks Ways to Take Sting Out of Sunburn

    If you've hit the beach, chances are you've experienced an unfortunate rite of summer: The sunburn. Skin so swollen it hurts to bend. The heat that rises from redden...

  2. Natural remedies for sunburn

    When summer hits, people emerge from their indoor environments and spend a lot more time outdoors enjoying the fine weather. Beaches and parks become highly popular,...

  3. Why we sunburn

    Sunburns readily advertise that we've had fun in the sun, and perhaps have been a bit careless, but what exactly goes on in our cells to produce the painful, red inf...

  4. CDC: Half of young adults get sunburned

    Half of U.S. adults under 30 say they have had a sunburn at least once in the past year, a government survey found - a sign young people aren't heeding the warnings ...

  5. Sun exposure and your health: The good, bad and the ugly

    It’s summer, and time to get outside. But before you do, you may be wondering if getting some sun is really good for you.Should you cover up or let it all hang out?W...

  6. How to keep your kid healthy this summer

    Summer’s right around the corner and as the weather warms up and your kids get ready for endless days at the beach, pool and park, keeping them healthy is your top p...

  7. Consumer group flags high SPF ratings on sunscreen as misleading

    Sunbathers headed to the beach this summer will find new sunscreen labels on store shelves that are designed to make the products more effective and easier to use. B...

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