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Bisphosphonates

No link seen between bone drugs, colon cancer

Women who use certain bone-building drugs may not have a decreased risk of colon cancer, a new study finds -- despite prior evidence suggesting the drugs might offer some protection.The drugs, called bisphosphonates, include brands like Fosamax, Boniva, Reclast and Actonel, along with generic versions.They are used to prevent and treat the bone-thinning disease osteoporosis, which mainly strikes older women. The drugs can also be used to help treat cancer that has spread to the bone from other sites in the body.Bisphosphonates have been tied to both good and bad side effects.Research has found after years of use, the drug may, in rare cases, actually weaken the bones and lead to thighbone fractures or a painful breakdown of the jaw bone.On the other hand, several studies have suggested women who use bisphosphonates may have a decreased risk of developing breast or colon cancer.But this latest study, reported in the Journal of Clinical Oncology, found no evidence that women on the medic...

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  1. Bone drugs linked to rare thigh fractures

    Widely used osteoporosis drugs such as Fosamax and Actonel significantly raise the risk for a rare but serious thigh fracture and that risk rises the longer patients...

  2. FDA Advisers Consider Time Limit for Bone Drugs

    Health advisers are considering a time limit for taking a class of drugs used by millions of women to prevent bone fractures, due to concerns over unusual fractures ...

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  4. FDA approves generic Boniva for osteoporosis

    The first generic versions of Roche's bone-strengthening drug Boniva have been approved by the U.S. Food and Drug Administration .Boniva, known generically as ibandr...

  5. More Unusual, Fewer Usual Breaks With Bone Drugs

    Women who take bone drugs for several years have a slightly increased chance of suffering an unusual type of thigh fracture, according to a large Canadian study.The ...

  6. Woman's Suit Claims Osteoporosis Drug Destroyed Her Jaw

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  7. Widespread use of prescription steroids draws worry

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