Wednesday, April 7, 2010 as of 11:14 AM ET
Rosiglitazone is an antidiabetic drug in the thiazolidinedione class of drugs. It works as an insulin sensitizer, by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin.
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S. drugs regulators will decide on Thursday whether GlaxoSmithKline Plc's diabetes drug Avandia should be pulled from the market due to concerns about heart risks. Here are some questions and answers about Avandia: What's the problem with this drug?Both Avandia, known generically as rosiglitazone, and rival drug Actos, or pioglitazone, made by Takeda Pharmaceutical Co Ltd, are known to raise the risk of heart failure. But Glaxo's drug has also been linked to an increased risk of heart attacks, following publication of a study in 2007 by Dr. Steve Nissen of the U.S. Cleveland Clinic, whose findings prompted the latest safety concerns. In an update to his original 2007 study in June this year, Nissen said a "meta-analysis" of 56 trials involving 35,000 people taking diabetes drugs showed those taking Avandia were between 28 percent and 39 percent more likely to have a heart attack. Debate about Avandia's safety has raged since 2007. Other research has provided conflicting ...LONDON (AP) — GlaxoSmithKline's controversial diabetes pill Avandia should be pulled from the U.K. market because of concerns that the drug can increase the risk of ...
The diabetes drug Avandia has been ordered off the market in Europe. But it will still be available in the United States – amid some tough new restrictions.Regulator...
LONDON (AP) — European Medicines Agency says diabetes drug Avandia should be pulled from market.
Diabetes medicine, Avandia , linked to heart disease
Hearings begin Tuesday on whether the drug Avandia should stay on the market.Ahead of the hearings, FDA scientists have blasted a study by drug maker GlaxoSmithKline...
New research sends a stark warning to overweight teens: If you develop diabetes, you'll have a very tough time keeping it under control.A major study, released Sunda...
Beginning in November, the popular diabetes drug, Avandia , will be removed from your local pharmacy’s shelves, the federal government said Tuesday. The new program ...
Warnings for two popular prescription drugs used by millions of Americans to treat osteoporosis and diabetes
The fate of a GlaxoSmithKline Plc diabetes drug may become clearer on Wednesday when U.S. advisers vote on whether the widely used pill carries too much heart risk t...
Commonly used diabetes drugs such as metformin may help control lung cancer , and may help prevent it, U.S. researchers reported on Tuesday.Patients who had taken th...
Company agrees to $3B deal over controversial diabetes drug Avandia
A review by federal health scientists reinforces potential ties between the diabetes pill Avandia and heart attack and death, opening the door for government action,...
GlaxoSmithKline's diabetes drug Avandia was no riskier to the heart than a rival, U.S. researchers said on Tuesday, a finding that contradicts earlier studies and ad...
Confidential U.S. government reports recommend that GlaxoSmithKline Plc's diabetes drug Avandia be pulled from the market because it can hurt the heart, The New York...
Three influential groups of doctors who treat diabetes urged patients not to stop taking Avandia , saying on Thursday that while news about the controversial drug ma...
Eric Yaverbaum and Guy Benson on which campaign is on message
Federal health officials are barring new patients from enrolling in a safety study of GlaxoSmithKline's controversial diabetes pill Avandia , a week after a panel of...
Risks from Avandia are great enough to "put you in a hospital or in a cemetery.” That’s a direct quote from Dr. David Graham, the lead author of a study, that ultima...
GlaxoSmithKline PLC said Monday it has updated the labeling of its diabetes pill Avandia to include safety restrictions ordered by federal health authorities because...
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