The Food and Drug Administration has approved a form of spray-on estrogen called Evamist, which treats moderate to severe menopausal symptoms, it is being reported in Obstetrics & Gynecology.
Evamist contains estrodial in ethanol and is formulated to be released over a 24-hour period, according to the report. The formula is applied on the inside of the female’s forearm and dries clear in one minute.
Experts say it cannot be washed off and it won’t transfer to other people.
“This estrodial ‘spray-on-patch’ is a treatment for women who will benefit from the advantages of transdermal estrodial delivery but are intolerant of or are not inclined to use patches, gels, or emulsions,” wrote Dr. John E. Buster and his colleagues from Brown University in Providence, Rhode Island.
In a study testing the product, a group of 454 women with at least eight moderate to severe hot flashes per day were randomly assigned to receive one, two, or three sprays of Evamist or a placebo each day.
The group receiving the spray showed significant reductions in the rate of occurrence and severity of hot flashes as compared to the group receiving the placebo.
Evamist is marketed by Ther-Rx Corporation.