A rare brain infection spread in freshwater lakes, rivers and hot springs killed six boys in three states last year, according to a report released by the U.S. Centers for Disease Control and Prevention; it is being reported by newsday.com.

The infection, which is known as primary amebic meningoencephalitis, struck 121 people in 15 southern states in the last 71 years. It usually affects boys, and in the months of July, August and September, according to newsday.com.

The infection occurs when an amoeba known as Naegleria fowleri goes up the nose and into the brain, the Web site reported.

The six people who died in 2007 lived in Florida, Texas and Arizona.

"An updated and consistent approach to N. fowleri risk-reduction messages, diagnosis and treatment is needed," the CDC said in its report.

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