Our guests this week:

• Sen. Jon Kyl, R-Ariz., Republican whip and McCain surrogate
• Sen. Chris Dodd, D-Conn., Obama surrogate
• Karl Rove, former White House senior adviser and FOX News contributor

Sen. Hillary Clinton won the West Virginia primary handedly, but many see that as a small victory with the numbers not in her favor to win the nomination. Frontrunner Sen. Barack Obama meanwhile has quietly started to shift focus to the general election in November where the Democratic nominee will face off against Sen. John McCain.

How will a general election look between Sens. McCain and Obama? How do these two candidates differ and where are they on the key voting issues of national security, the economy, taxes and health care? We'll ask all this and much more with McCain supporter and Republican Whip, Sen. Jon Kyl, R-Ariz., along with key Senate surrogate to the Obama campaign, Sen. Chris Dodd, D-Conn.

Plus, the Republican Party has seen three congressional seats go to the Democrats since March. What is the state of the Republican Party and what can they do to hold on to their seats in November? We'll sit down with Karl Rove, former White House senior adviser to President Bush and current FOX News contributor.

And, our Power Player of the Week has won the Kentucky Derby and has his eyes set on the Triple Crown. "FOX News Sunday" goes to the races with Kentucky Derby winner Big Brown's trainer, Rick Dutrow, Jr.

So check your local listings and we’ll see you on the next "FOX News Sunday."