Drexler and his professional partner, Elena Grinenko, earned a paltry 13 points out of 30 — plus harsh words from the judges — for their performance of the rumba.
"You're the worst dancer in this competition," judge Carrie Ann Inaba said, "and tonight was really bad."
Still, Drexler kept a smile on his face, graciously thanking the judges, his partner, his fellow contestants and the fans when he learned he was this week's celebrity casualty.
"I want to thank the fans who voted and kept us in the competition," he said. "Lord knows they were keeping us in."
Each week, judges' scores are combined with viewer votes to determine which couple will be eliminated. Drexler and Grinenko were among the lowest-scorers throughout this season's dance-off.
Grammy-winner Macy Gray also performed, singing her new single, "Finally Made Me Happy," which she dedicated to the victims of the Virginia Tech shooting.
Paulina Porizkova, Shandi Finnessey and Leeza Gibbons have already been eliminated. The remaining celebrity dancers are Billy Ray Cyrus, Ian Ziering, Joey Fatone, Laila Ali, John Ratzenberger, Heather Mills and Apolo Anton Ohno. All will perform a group swing dance on next week's show.