The festival, which will run from April 25 through May 5, is taking the rare step of opening not with a high-profile feature film but seven short films presented by the Save Our Selves (SOS) campaign.
"The SOS Short Films Program harnesses some of the world's most creative minds to educate, inform and inspire people across the globe to solve the climate crises," former Vice President Gore said Thursday in a statement. "Premiering the SOS films at Tribeca will ensure that these pieces will be viewed all over the world for years to come."
It was also announced that "The Gates" will close the festival on May 5. Produced by HBO, "The Gates" documents Christo and Jeanne-Claude's artwork that raised 7,500 fabric-paneled gates in New York's Central Park in 2005.
The 12-day festival will also feature the world premiere of "Lucky You," directed by Curtis Hanson ("L.A. Confidential," "Wonder Boys") on May 1. The romance stars Eric Bana, Drew Barrymore and Robert Duvall.
It was earlier announced that "Spider-Man 3" will make its U.S. premiere at the festival on April 30.
This is the sixth annual Tribeca Film Festival, which was founded in 2002 by Robert De Niro and Jane Rosenthal to help rejuvenate Lower Manhattan following the terrorist attacks on the World Trade Center.