The Material Mom is desperately seeking a Malawian girl.
"Yes, absolutely. I'm going to adopt another Malawian child very quickly. A baby girl this time, in order to redress the balance," the 48-year-old singer-turned-Angelina Jolie wannabe told Paris Match.
She said her two other children, Lourdes and Rocco, would be given a "choice" in selecting their new sister like picking candy off a store shelf.
But she first wanted them to get used to their new baby brother, 13-month-old David Banda, whom Madonna is in the process of adopting.
Madonna flew the little boy from a Malawian orphanage to England last month to live with her and her filmmaker husband Guy Ritchie.
But Madonna took a severe beating in the media and among charitable groups when it emerged that she had been allowed to take the boy out of the country in violation of the nation's rules regarding adoptions.
Then the boy's father -- who had placed his son in the orphanage after his wife had died -- turned on the pop star, saying he didn't fully understand the papers he had signed. He then once again offered his support to the star and asked her not to change her mind about the adoption.
A judge is set to rule next week on whether to allow the controversial adoption.
Madonna, however, steadfastly defended herself.
"I saved this child from certain death. There is nothing more important in my eyes than that. I love David like a son," she said.
"Of course, after some time, I intend to return David to his home so that he can get to know his biological father and so that he can discover his homeland."
The Material Mom told the French magazine that she was surprised at how people had reacted.
"It was not me who chose Malawi, but it chose me," she said. "A native of the country contacted me through my association, Spirituality for Kids, which I publicize in all my shows.
"She helps a lot of orphans in Malawi and she told me about the childhood poverty, and the dreadful mortality rate," she continued.
"She asked me for help as my fame could help focus on the problems. I started my own inquiry and said to myself, 'They need help!' "