"In the most troubled parts of the world — places that much of the world has abandoned — MSF is always there," said Jolie in a statement issued by Trevor Neilson, the couple's philanthropic and political adviser. "I have seen these brave men and women working in war zones and horrific conditions and I deeply admire them."
Jolie is a goodwill ambassador for the U.N. High Commission for Refugees.
Jennifer Delaney, U.S. director for Global Action for Children, expressed her thanks for the gift from the Jolie-Pitt Foundation.
"Angelina Jolie and Brad Pitt not only care, but more important, are taking concrete action to address the fact that there will be 20 million children orphaned by AIDS by 2010, and millions more orphaned by tuberculosis, malaria and conflict or whose parents are sick and dying," she said.
Delaney said the vast majority of these children are being cared by extended families and communities that need support to overcome the ravages of HIV/AIDS and poverty.