Another beautiful dream for TV's Dr. McDreamy. Patrick Dempsey and his wife, Jillian, are expecting their second child, Dempsey's publicist, Leslie Sloane Zelnik, said Wednesday.

The "Grey's Anatomy" star and his wife have a daughter, Talulah.

Dempsey, 40, plays Dr. Derek Shepherd, better known as the hunky Dr. McDreamy to his female colleagues on the hit ABC show.